Avmacol: Extra strength

289.00kr

What is Avmacol® Extra Strength?

Avmacol® Extra Strength is a patented, sulforaphane-producing supplement that works in combination with Maitake mushroom extract (Grifola frondosa) to support your body’s natural detoxification process better than sulforaphane alone1. Avmacol® Extra Strength provides glucoraphanin (sulforaphane glucosinolate) and active myrosinase enzyme which are the essential ingredients needed for sulforaphane production. Maitake mushroom extract has been found to provide immune support by promoting neutrophil function and natural killer cell activity.*

Sulforaphane promotes your body’s natural detoxification process for certain environmental threats found in the air you breathe, the food you eat, and the water you drink. Research has shown sulforaphane also supports the body’s defenses against oxidative stress and cell damage.*

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Description

About Avmacol®Extra Strength

  • Just One Tablet Daily
  • Promotes Your Body’s Natural Detoxification Process*
  • Contains Maitake mushroom extract (Grifola frondosa) for Immune Support*
  • Supports Long Lasting Antioxidant Activity*

Avmacol® Extra Strength may be swallowed or crushed and mixed with foods such as yogurt, applesauce or smoothies for easier consumption.

 

Additional Information:

  • Vegetarian Formula
  • Gluten-Free
  • No Generic Equivalent
  • Packaged in BPA-free bottles
  • Subject to more than 80 quality checks

 

Supplement Facts:

Serving Size Information: One (1) tablet daily.

Directions for Use: Take one (1) tablet per day with a meal. If you have a condition that requires medical attention always consult your physician before taking any dietary supplement.

Keep in a cool, dry place. Do not use if seal is broken or missing.

Importance of Active Myrosinase Enzyme

The conversion of glucoraphanin (sulforaphane glucosinolate) to sulforaphane can be expressed in this simple equation:

Active Myrosinase Enzyme

Active myrosinase enzyme is essential for the conversion of glucoraphanin (sulforaphane glucosinolate) to sulforaphane. Without this enzyme, it may not be possible to reap sulforaphane’s many health-promoting benefits, which is why you’ll always find active myrosinase enzyme in the Avmacol brand family.

Even though it is true that both glucoraphanin (sulforaphane glucosinolate) and the myrosinase enzyme can be found in cruciferous vegetables such as broccoli, Brussels sprouts, and cauliflower, there may not be enough of either compound to allow for adequate sulforaphane production. This can be due to seed quality, soil composition, and many other factors. Additionally, the myrosinase enzyme can be destroyed during the cooking process. So while both glucoraphanin (sulforaphane glucosinolate) and the myrosinase enzyme can be found in the vegetables you eat, the ones you buy from the market are not reliable sources of either compound.

The Avmacol brand contains both glucoraphanin (sulforaphane glucosinolate) and active myrosinase enzyme, the essential ingredients needed to promote sulforaphane production.*

How Avmacol® Extra Strength® works

Our Sulforaphane Production System® supplies glucoraphanin (sulforaphane glucosinolate) and active myrosinase enzyme which helps promote sulforaphane production in your body. As depicted in the diagram below, when sulforaphane enters your cells it allows for a master regulator, known as NRF2, to enter the nucleus and bind to DNA. This helps increase the production of important Phase 2 detoxifying enzymes, promoting your body’s natural detoxification process, thereby supporting the elimination of potentially harmful metabolites.*

The Maitake mushroom extract (Grifola frondosa) works in combination with sulforaphane to support your body’s natural detoxification process better than sulforaphane alone.1 In addition, the Maitake mushroom extract found in Avmacol® Extra Strength provides the added bonus of immune support by promoting neutrophil function and natural killer cell activity.

The Science Behind Avmacol Extra Strength

  • The combination of sulforaphane and Maitake extract supports the movement (or translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of certain Phase 2 enzymes. Below are images of a technique called immunofluorescence which illustrate how much protein is being produced in the cell and the location of that protein.

    Image 1

    In control cells (left panel), the green staining indicates that NRF2 remains largely in the cytoplasm (arrows) without much protein located in the nucleus, which is counter-stained in blue. When cells are exposed to sulforaphane and Maitake (right panel), NRF2 moves to the nucleus (arrows) where it can bind to DNA to turn on expression of certain Phase 2 enzymes.

    Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1

    Image 2

    In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount of protein, is increased.

    Image 3

    In control cells (left panel) HO-1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of HO-1 staining, representing the amount of protein, is increased.

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